Dual-band spectral filter array integrated with a telecentric lens for real-time surface plasmon resonance sensing and imaging

Simplified Abstract
To enable multispectral capabilities on standard cameras, we developed a dual-band spectral filter array (DSFA) platform for real-time SPR imaging. By using a pixel-shift algorithm and a silicon nanostructure, the system separates light into two channels for ϒ-based spectral contrast analysis. In biomolecular tests, this method improved refractive-index sensitivity by nearly 100 times compared to traditional wavelength-shift analysis. The result is a compact, label-free solution for high-performance quantitative sensing without requiring expensive integrated filter cameras.
Key Takeaways
•The Problem: High-end spectral imaging usually requires specialized, expensive sensors with built-in filters.
•The Innovation: A custom DSFA filter and ϒ-based algorithm that work with standard broadband cameras.
•The Impact: Achieved a two-order-of-magnitude increase in sensitivity for real-time molecular interaction monitoring.